Subcional JAK2 V617F

What does "Subcional JAK2 V617F" mean in a report or doctor's letter? In our medical dictionary, you will find a patient-friendly explanation of the meaning of this medical term.

Explanation

"Subclonal JAK2 V617F" refers to a specific change in a gene that is not present in all cells but only in a subset, hence the term "subclonal". The JAK2 gene is involved in the growth and development of cells, and the V617F change is a common mutation found in certain blood disorders. This mutation can cause the JAK2 gene to be more active than normal, leading to an overproduction of blood cells.

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