What does "Significant clubbing" mean in a report or doctor's letter? In our medical dictionary, you will find a patient-friendly explanation of the meaning of this medical term.
"Significant clubbing" in medicine refers to a noticeable change in the shape of your fingers and nails. It usually happens when the amount of oxygen in your blood is lower than normal. The ends of your fingers might look larger than normal and your nails may curve around your fingertips. This condition can be a sign of lung disease, heart disease, liver disease, or gastrointestinal disease.
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