Second pass

What does "Second pass" mean in a report or doctor's letter? In our medical dictionary, you will find a patient-friendly explanation of the meaning of this medical term.

Explanation

"Second pass" in medicine refers to the process where a drug, after being absorbed and circulated throughout the body, is processed again by the liver. This happens when a drug is taken orally, absorbed into the bloodstream, and then goes through the liver a second time before it reaches the rest of the body. This process can affect the amount of the drug that is available to have an effect on the body, as the liver can change or break down the drug during this second pass.

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