A sagittal plane is an imagined upright slice that runs from front to back, separating the body into right and left parts. On a scan, it gives a side-on view of the structures within that slice.
No. A sagittal slice can pass through the middle or lie to either side of it. A slice through the exact midline is called the median plane. Sagittal describes the direction of the view, not a disease or an abnormal finding.

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