PI-RADS in a prostate MRI report

Explanation

PI-RADS is a scoring system used when reading magnetic resonance imaging (MRI) scans of the prostate. It describes how suspicious an area looks for clinically significant prostate cancer. A score is not a confirmed cancer diagnosis.

What do the numbers mean?

Scores run from 1 to 5. PI-RADS 1 means a very low likelihood of clinically significant cancer, and 2 means a low likelihood. PI-RADS 3 means the finding is uncertain. Scores 4 and 5 indicate high and very high suspicion.

In this system, “clinically significant” refers to cancers with features such as more abnormal cells under the microscope, a larger tumour volume or growth beyond the prostate. These features can affect care decisions, but the MRI score alone does not decide treatment. PI-RADS 4 does not mean stage 4 cancer.

What happens after the scan?

The report also describes where an abnormal area is and how large it is. Your doctor considers the complete report alongside the reason for the scan and your medical history when discussing further tests or follow-up.

An MRI cannot always tell cancer apart from inflammation or changes after a previous procedure. A low score also does not provide an absolute guarantee that no cancer is present. Ask which finding needs follow-up and what the proposed next step is intended to clarify.

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