A stool chymotrypsin test measures a digestive enzyme released by the pancreas.
Chymotrypsin is an enzyme released by the pancreas that helps digest protein from food. Some of the enzyme can be measured in a stool sample. The test may be used when a clinician is investigating whether the pancreas is supplying enough digestive enzymes.
A low stool chymotrypsin result may support concern about reduced pancreatic enzyme supply, but it does not identify the underlying condition on its own. The result is interpreted with symptoms and other tests. The laboratory’s collection instructions and reference range should be used.

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