Calprotectin stool test
Explanation
A calprotectin test measures a protein in a stool sample. Certain white blood cells release this protein when the intestines are inflamed. The result helps assess whether bowel symptoms may involve inflammation, but it does not identify the cause on its own.
Does a high result mean Crohn's disease?
No. Crohn's disease and ulcerative colitis are long-lasting conditions that cause inflammation in the bowel. They can raise calprotectin, but intestinal infections and some medicines can raise it too. The result may help decide whether further investigation is needed. It can also help monitor known inflammatory bowel disease.
What does a low result mean?
A low result makes significant intestinal inflammation less likely. It does not explain every possible cause of bowel symptoms, and inflammation can occasionally be present despite a normal result. Your symptoms and other findings still matter.
What should I mention before the test?
Tell your clinician about medicines such as ibuprofen and treatments that reduce stomach acid. Follow the sample collection instructions and do not stop prescribed medicine without advice. Ask whether a repeat sample or further testing is needed for your result.
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