Anti-DNase B blood test

Explanation

Anti-DNase B measures antibodies against a substance made by group A streptococcal bacteria. Antibodies are proteins made by the immune system. The result can help show that a streptococcal infection occurred previously.

Why look for a past infection?

Some illnesses can develop after a streptococcal infection has passed. When investigating certain kidney or inflammatory problems, the clinician may need evidence of an earlier infection even if the original sore throat or skin infection has gone.

Anti-DNase B may be assessed with another antibody test called ASO. The two antibody responses develop differently, and anti-DNase B can be helpful after a skin infection.

Does a high result mean I still have the bacteria?

No. The test measures an immune response, not living bacteria. A high value alone does not show that an infection is still active or that antibiotics are needed. Symptoms, timing and other test results determine its meaning.

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